苏艳霞,高汝钦.正己烷非神经毒性作用研究进展[J].济宁医学院学报,2021,44(5):362-366 |
正己烷非神经毒性作用研究进展 |
Research progress on non-neurotoxic effects of n-hexane |
投稿时间:2021-02-22 |
DOI:10.3969/j.issn.1000-9760.2021.05.014 |
中文关键词: 正己烷;非神经毒性 |
英文关键词: N-hexane;Non-neurotoxic effect |
基金项目: |
作者 | 单位 | E-mail | 苏艳霞 | 青岛大学公共卫生学院, 青岛 266071 | | 高汝钦 | 青岛大学公共卫生学院, 青岛 266071 青岛市疾病预防控中心, 青岛 266033 | gaoruqin@sohu.com |
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中文摘要: |
正己烷作为一种用途广泛的有机溶剂,在作业环境中可通过呼吸系统进入机体而产生毒性作用。目前对正己烷毒性作用的关注点主要集中在神经系统的损伤、损伤机制及防治等方面。最近的研究发现,正己烷可造成神经系统以外包括肝脏、肺脏、肾脏、生殖系统在内的多个脏器和系统的非神经毒性作用。本文结合国内外相关文献,对正己烷的非神经毒性作用的研究进展做一综述,旨在为正己烷毒性作用的总体评价和防治提供依据。 |
英文摘要: |
As a widely used organic solvent, N-hexane can enter the body through the respiratory system and produce toxic effects in working environment.At present, the researches on toxic effect of n-hexane mainly focus on the injury of nervous system and its mechanism, prevention and treatment.Recent studies have found that n-hexane can cause non-neurotoxic effects, including the toxic effects of liver, lung, kidney and reproductive system.In this paper, the research progress on non-neurotoxic effects of n-hexane were reviewed for providing evidence for the general evaluation and prevention of n-hexane toxicity. |
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