| 黄言,梁秋华.硫化氢抑制动脉钙化的研究进展[J].济宁医学院学报,2022,45(6):444-447 |
| 硫化氢抑制动脉钙化的研究进展 |
| Research progress in the inhibition of arterial calcification by hydrogen sulfide |
| 投稿时间：2022-03-24 |
| DOI：10.3969/j.issn.1000-9760.2022.06.014 |
| 中文关键词: 硫化氢;动脉钙化;信号通路 |
| 英文关键词: Hydrogen sulfide;Arterial calcification;Signal pathway |
| 基金项目:国家自然科学基金青年基金(81400860);山东省自然科学基金面上项目(ZR2019MH087) |
| 作者 | 单位 | E-mail | | 黄言 | 济宁医学院临床医学院, 济宁 272013
济宁医学院附属医院, 济宁 272029 | | | 梁秋华 | 济宁医学院临床医学院, 济宁 272013
济宁医学院附属医院, 济宁 272029 | liangqiuhua_meta@163.com |
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| 中文摘要: |
| 动脉钙化是一种导致动脉血管硬化和功能障碍的疾病,可以导致不良心血管事件的发生,常见于衰老、慢性肾脏病、糖尿病等。硫化氢是一种气体信号分子,既可以引起中毒也可以抗炎、抗氧化、抗凋亡。近年来发现硫化氢可以通过多种机制抑制动脉钙化。本文就近年来硫化氢抑制动脉钙化的机制研究做一综述,以期为治疗动脉钙化提供新的思路。 |
| 英文摘要: |
| Arterial calcification is a disease that leads to arteriosclerosis and dysfunction that may cause adverse cardiovascular events.It is common in aging,chronic kidney disease,diabetes and so on.Hydrogen sulfide is a kind of gas signal molecule which can not only cause poisoning but also anti-inflammatory,anti-oxidation and anti-apoptosis.In recent years,it has been found that hydrogen sulfide can inhibit arterial calcification through a variety of mechanisms.This article reviews the mechanism of hydrogen sulfide inhibiting arterial calcification in recent years in order to provide new ideas for the treatment of arterial calcification. |
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