| 【Abstract】Objective: To investigate the efficacy of evidence-based bundled nursing interventions in improving diarrhea and nutritional status among patients with intracranial injuries receiving enteral nutrition. Methods: Using random number tables, 103 patients with intracranial injury receiving enteral nutrition admitted to our neurosurgery department from January 2024 to May 2025 were divided into an observation group (evidence-based bundled nursing intervention, n=51) and a control group (conventional enteral nutrition care, n=52). After 14 days of intervention, we analyzed the following during the care period: neurological function indicators before and after intervention [glial fibrillary acidic protein (GFAP), ubiquitin carboxy-terminal hydrolase-1 (UCH-L1)], nutritional status before and after intervention (serum albumin, hemoglobin, serum total protein), and complication incidence (gastric retention, constipation, aspiration, abdominal distension/pain, nausea, overall incidence rate). Results: During the nursing period, the incidence of watery stools (7.84%) and diarrhea (9.80%) in the observation group were lower than those in the control group (all P < 0.05). The onset time of diarrhea was delayed and the duration was shorter in the observation group compared to the control group (all P < 0.05). Post-intervention, the observation group exhibited lower UCH-L1 and GFAP levels than the control group (all P < 0.05). Post-intervention, the control group had lower serum total protein, serum albumin, and hemoglobin levels than the observation group (all P < 0.05). The overall complication rate during the nursing period was lower in the observation group (13.72%) than in the control group (36.54%) (P < 0.05). Conclusion: The application of evidence-based bundled nursing interventions for enteral nutrition in patients with traumatic brain injury effectively reduces diarrhea incidence, decreases watery stool frequency, delays the onset of first diarrhea, shortened the duration of diarrhea, lowered the concentration of brain-specific injury factors, and improved nutritional status and complication rates. These findings warrant clinical implementation. |
