| 张浩,董楷,崔健,李龙飞,刘传新.抑郁症主客观认知功能的网络特征及其与社会功能的关系[J].济宁医学院学报,2026,49(1):11-17 |
| 抑郁症主客观认知功能的网络特征及其与社会功能的关系 |
| Network analysis of subjective and objective cognitive functions in depression and its correlation with social functioning |
| 投稿时间：2025-09-01 |
| DOI：10.3969/j.issn.1000-9760.2026.01.003 |
| 中文关键词: 抑郁症;主观认知功能;客观认知功能;网络分析;社会功能 |
| 英文关键词: Depression;Subjective cognitive function;Objective cognitive function;Network analysis;Social functioning |
| 基金项目:国家科技创新2030-“脑科学与类脑研究”重大项目2021年度定向委托项目(2021ZD0200600) |
| 作者 | 单位 | E-mail | | 张浩 | 济宁医学院精神卫生学院, 济宁 272013 | | | 董楷 | 济宁医学院精神卫生学院, 济宁 272013 | | | 崔健 | 山东省戴庄医院精神科, 济宁 272051 | | | 李龙飞 | 山东省戴庄医院精神科, 济宁 272051 | | | 刘传新 | 济宁医学院精神卫生学院, 济宁 272013 | liuchuanxin2003b@163.com |
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| 中文摘要: |
| 目的 本研究旨在识别抑郁症主客观认知功能的核心症状，同时识别出认知功能与社会功能相关症状。方法 选取2023年2月—2024年10月在山东省戴庄医院就诊的181名抑郁症患者为研究对象。抑郁症认知损害5项问卷(Five-item Perceived Deficits Questionnaire for Depression, PDQ-5-D)、中国简版神经认知成套测验(Chinese Version of Brief Neurocognitive Test Battery, C-BCT)、席汉残疾量表(Sheehan Disability Scale, SDS)用于评定主观认知功能、客观认知功能以及社会功能。使用R软件对网络进行统计分析和可视化。结果 大脑空白为主观认知网络及客观认知网络中的中心症状和桥接症状。难条理化与社会功能之间存在相关性。性别与网络全局强度、边权重分布或个体边权重无关。结论 大脑空白是整个主客观认知网的核心症状。难条理化与社会功能间关联系数最高。关注大脑空白症状，可能在一定程度上改善抑郁症患者的认知功能。通过及早干预并改善难条理化症状，或将更好改善患者的社会功能。 |
| 英文摘要: |
| Objective This study aims to identify the core symptoms of subjective and objective cognitive functions in patients with depression, while revealing symptoms associated with cognitive and social functions. Methods A total of 181 patients with depression, diagnosed at Daizhuang Hospital in Shandong Province from February 2023 to October 2024, were enrolled.Subjective cognitive function was assessed using the Five-item Perceived Deficits Questionnaire for Depression (PDQ-5-D); objective cognitive function using the Chinese Version of the Brief Neurocognitive Test Battery (C-BCT); and social function using the Sheehan Disability Scale (SDS).Network statistical analysis and visualization were performed using R software. Results The blank mind serves as the central symptom and bridging node in both the subjective cognitive network and the objective cognitive network.The difficulty in organization is associated with social function.Gender shows no relation to the network's global strength, edge weight distribution, or individual edge weights. Conclusion Brain fog is the core symptom in the subjective-objective cognitive network.The symptom difficulty in organization showed the strongest correlation with social function.Clinically, targeting brain fog may improve cognitive function in patients with depression to some extent.Early intervention to address difficulty in organization may enhance patients' social function. |
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