| 周艺彤,王冠男.无机纳米材料用于动脉粥样硬化的诊断和治疗[J].济宁医学院学报,2025,48(3):273-278 |
| 无机纳米材料用于动脉粥样硬化的诊断和治疗 |
| Inorganic nanomaterials for diagnosis and treatment of atherosclerosis |
| 投稿时间：2024-09-25 |
| DOI：10.3969/j.issn.1000-9760.2025.03.018 |
| 中文关键词: 无机纳米材料;动脉粥样硬化;诊断;治疗 |
| 英文关键词: Inorganic nanomaterials;Atherosclerosis;Diagnosis;Therapy |
| 基金项目:沈阳医学院高层次人才引进(310010029009) |
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| 摘要点击次数: 13 |
| 全文下载次数: 5 |
| 中文摘要: |
| 动脉粥样硬化(atherosclerosis,AS)在世界范围内越来越普遍,其相关疾病已成为导致死亡的主要原因之一。目前AS的临床治疗方法主要包含药物治疗和手术治疗。药物治疗(如他汀类药物等)可能会引起肝功能损害、消化道出血、肌肉不适、心律失常等不良反应。手术治疗(如内膜剥脱术、球囊扩张术或支架植入术等)还可能导致术后再狭窄等预后问题。因此,早发现、早诊断、早治疗应该是AS首要的关注策略。近些年来,无机纳米材料由于其独特的性质(例如超顺磁性、光响应性、小尺寸效应等)引起了研究人员的广泛关注,并被认为是开发改进AS治疗策略的关键。因此,本综述将近些年来用于成像和治疗AS的无机纳米材料进行了分类总结。 |
| 英文摘要: |
| Atherosclerosis (AS) is becoming increasingly prevalent worldwide,with related diseases now a leading cause of death.Current clinical treatment methods for AS mainly include drug treatment and surgical treatment.Drug therapy (such as statins) may lead to adverse reactions like liver damage, gastrointestinal bleeding,muscle discomfort,and arrhythmias.Surgical treatments (such as endarterectomy,angioplasty,or stent implantation) may also result in postoperative restenosis and other prognosis issues.Therefore,early detection,diagnosis,and treatment should be the primary focus for atherosclerosis.In recent years,inorganic nanomaterials have garnered significant attention from researchers due to their unique properties (eg,superparamagnetism,photoresponsiveness, small size effects) and are considered crucial for developing improved strategies for atherosclerosis treatment.Hence,this review categorizes and summarizes the use of inorganic nanomaterials for imaging and treating AS in recent years. |
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