| 乔保俊,胡良晨,郝延磊.卒中危险因素的研究与预防[J].济宁医学院学报,2017,40(5):382-388 |
| 卒中危险因素的研究与预防 |
| The research and prevention of stroke risks |
| 投稿时间：2017-07-28 |
| DOI：10.3969/j.issn.1000-9760.2017.05.016 |
| 中文关键词: 卒中;危险因素;预防 |
| 英文关键词: Stroke;Risk factors;Prevention |
| 基金项目:济宁医学院基金孵育项目。 |
| 作者 | 单位 | E-mail | | 乔保俊 | 济宁医学院附属医院, 济宁 272029 | | | 胡良晨 | 济宁医学院附属医院, 济宁 272029 | | | 郝延磊 | 济宁医学院附属医院, 济宁 272029 | yhao@mail.jnmc.edu.cn |
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| 中文摘要: |
| 卒中是我国目前致死、致残的首位原因，可以导致社会与家庭的沉重经济负担。对卒中危险因素及预防的研究对降低卒中的发病率具有重要意义。近年的研究发现与缺血型卒中相关的危险因素分别为：高血压、吸烟、腰臀比、饮食、体育运动、糖尿病、大量饮酒、心理压力和抑郁、心脏疾病、载脂蛋白B与载脂蛋白A1比值；与出血型卒中相关的危险因素为：高血压、吸烟、腰臀比、饮食和大量饮酒。此外，炎症与感染和遗传因素在卒中发病中的作用也越来越受到人们的重视。除了针对高血压、糖尿病等靶向危险因素的干预外，越来越多的研究显示行为、生活方式的干预是预防卒中的基石。 |
| 英文摘要: |
| In China,the economic burden of stroke is high,with stroke remaining the leading cause of adult disability and death.Reducing the incidence of stroke requires identification of modifiable risk factors and demonstration of the efficacy of risk reduction efforts.Recent studies have demonstrated that risk factors for ischemic stroke include hypertension,current smoking,waist-to-hip ratio,diet risk score,regular physical activity,diabetes mellitus,binge alcohol consumption,psychosocial stress and depression,cardiac disease,and ratio of apolipoprotein B to A1.While hypertension,smoking,waist-to-hip ratio,diet,and heavy alcohol consumption are all associated with intracerebral hemorrhage.In addition,the role of inflammation,infection and genetic factors in the pathogenesis of stroke is more and more valued by people.Besides targeting prevention factors such as hypertension,diabetes mellitus,cardiac disease and so on,behavioral modification is the cornerstone of lifetime risk reduction. |
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