| 岳屹囡,孙绪丁.甲泼尼龙联合免疫球蛋白治疗小儿重症病毒性脑炎临床观察[J].济宁医学院学报,2013,(1):34-36 |
| 甲泼尼龙联合免疫球蛋白治疗小儿重症病毒性脑炎临床观察 |
| Comparison of the effects of different-doses of methylprednisolone sodium succinate and human immunoglobulin on viral encephalitis in children |
| 投稿时间：2012-10-11 |
| DOI：10.3969/j.issn.1000-9760.2013.01.009 |
| 中文关键词: 病毒性脑炎;甲泼尼龙;免疫球蛋白;剂量 |
| 英文关键词: Viral encephalitis;Methylprednisolone Sodium Succinate;Human Immunoglobulin;dose |
| 基金项目: |
| 作者 | 单位 | | 岳屹囡 | 济宁医学院附属济宁市第一人民医院, 山东济宁 272011 | | 孙绪丁 | 济宁医学院附属济宁市第一人民医院, 山东济宁 272011 |
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| 中文摘要: |
| 目的 探讨冠状动脉粥样硬化与颈动脉粥样硬化之间的相关性。方法 选择本院就诊行64排冠脉CT(computed tomography,CT)检查的患者110例,分为对照组和冠心病组,并对冠心病组的冠脉狭窄进行分级、计算冠状动脉斑块积分。应用超声对双侧颈动脉进行检查,测量两组患者颈动脉内中膜厚度(intima-media thickness,IMT)及斑块厚度。结果 冠心病组74例有颈动脉粥样硬化病变的67例,占91%,对照组36例有颈动脉粥样硬化病变的9例,占25%,差异有显著性意义(P<0.05)。冠心病组颈动脉IMT、颈动脉斑块积分及冠状动脉斑块积分明显高于对照组,差异有显著性意义(P<0.05)。冠状动脉粥样硬化斑块积分与颈动脉斑块厚度积分呈正相关(r=0.902,P<0.05)。结论 冠状动脉粥样硬化与颈动脉粥样硬化程度呈正相关。 |
| 英文摘要: |
| Objective To investigate the effects of different-doses of Methylprednisolone Sodium Succinate and Human Immunoglobulin on viral encephalitis in children.Methods 90 patients with viral encephalitis were selected on standard,and randomly divided into two groups:group A (n=60) and group B (n=30).The children in group A were given Methylprednisolone Sodium Succinate 10~15 mg·kg-1 ·d-1 for 3~5 days and Human Immunoglobulin 0.5~0.7 g·kg-1 ·d-1 for 3 days by intervenous drop infusion.The children in group B were given Methylprednisolone Sodium Succinate 2~3 mg·kg-1 ·d-1 for 3~5 days and Human Immunoglobulin 0.3~0.4g·kg-1 ·d-1 for 5 days by intervenous drop infusion.Results The extinction time of fever and symptom in chrilren with viral encephalitis in group A was significantly shorter than those in group B(P<0.01).Conclusion It is reasonable to use full-dose Methylprednisolone Sodium Succinate and full-dose Human Immunoglobulin in short time to treat serious viral encephalitis.Key words:Viral encephalitis; Methylprednisolone Sodium Succinate; Human Immunoglobulin; dose |
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